Description

5-Piperidin-1-Yl-Thiophene-2-Carbaldehyde is a versatile heterocyclic building block featuring a thiophene core substituted with a piperidine and an aldehyde functional group. This compound is of significant value in medicinal chemistry and advanced materials research due to its unique molecular architecture, which serves as a key intermediate for constructing complex pharmacophores. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiophene-piperidine scaffold can contribute to novel modes of action.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and liquid crystals due to the electron-rich thiophene unit.
• Chemical Biology: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and tool compounds for biological pathway investigation.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	5-Piperidin-1-Yl-Thiophene-2-Carbaldehyde
CAS No.	24372-48-3
Molecular Formula	C10H13NOS
Molecular Weight	195.28 g/mol
Synonyms	5-(1-Piperidinyl)-2-thiophenecarboxaldehyde; 5-(Piperidin-1-yl)thiophene-2-carbaldehyde; 2-Formyl-5-piperidin-1-ylthiophene; 5-Piperidin-1-ylthiophene-2-carboxaldehyde; Thiophene-2-carboxaldehyde, 5-(1-piperidinyl)-; 24372-48-3; 5-Piperidin-1-yl-2-thiophenecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Piperidin-1-Yl-Thiophene-2-Carbaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to preserve aldehyde functionality.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.