Description

2-Butyltetrahydro-2H-1,3,2-Oxazaborine is a specialized organoboron compound, specifically a cyclic oxazaborolidine. This chemical is valued for its role as a versatile catalyst and chiral auxiliary in advanced organic synthesis, enabling highly selective chemical transformations. It is primarily sought by research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers working on asymmetric synthesis, including the production of active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Asymmetric Catalysis: Employed as a chiral catalyst or catalyst precursor in enantioselective reduction reactions, such as the borane-mediated reduction of prochiral ketones.
• Pharmaceutical Synthesis: A key intermediate or auxiliary in the synthesis of chiral drug molecules, contributing to the production of single-enantiomer pharmaceuticals.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals where precise stereochemical control is required.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and process chemistry R&D.
• Polymer Chemistry: Potential use as a modifying agent or initiator in the synthesis of polymers with specific stereoregular structures.

Basic Information

Product Name	2-Butyltetrahydro-2H-1,3,2-Oxazaborine
CAS No.	24372-00-7
Molecular Formula	C7H15BNO
Molecular Weight	140.01 g/mol
Synonyms	2-Butyl-1,3,2-oxazaborolidine; 2-n-Butyl-1,3,2-oxazaborolidine; 2-Butyl-2H-1,3,2-oxazaboroline, tetrahydro-; Oxazaborolidine, 2-butyltetrahydro-; B-Butyloxazaborolidine; 2-n-Butyloxazaborolidine; Borane, (tetrahydro-2-(1-methylethyl)-2H-1,3,2-oxazaborol-2-yl)- (related); (S)-2-Butyl-1,3,2-oxazaborolidine (chiral variant)
EINECS	Contact for details

Quality Control

Our 2-Butyltetrahydro-2H-1,3,2-Oxazaborine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including NMR, GC, and HPLC analysis, to verify chemical identity and purity. Certificates of Analysis (COA) are available upon request for all shipments, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.