Description

N(4)-Acetylsulfadimethoxine is a key acetylated derivative of the sulfonamide antibiotic sulfadimethoxine. This compound serves as a critical intermediate in pharmaceutical synthesis and analytical research, offering a stable, protected form for further chemical modifications. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, veterinary medicine, and analytical chemistry sectors for the development and quality control of antimicrobial agents.

Application

• Pharmaceutical Intermediate: A vital building block in the synthesis of sulfonamide-based antibiotics and other active pharmaceutical ingredients (APIs).
• Veterinary Drug Research: Used in the development and study of long-acting antibacterial treatments for animals.
• Metabolite Standard: Serves as a reference standard in analytical laboratories for the identification and quantification of sulfadimethoxine and its metabolites in biological and environmental samples.
• Biochemical Research: Employed in studies investigating the mode of action, resistance mechanisms, and metabolic pathways of sulfonamide drugs.
• Quality Control & Compliance: Essential for regulatory testing and method validation to ensure the purity and safety of pharmaceutical products.

Basic Information

Product Name	N(4)-Acetylsulfadimethoxine
CAS No.	24341-30-8
Molecular Formula	C14H16N4O5S
Molecular Weight	352.37 g/mol
Synonyms	4-Acetylsulfadimethoxine; N4-Acetylsulfadimethoxine; Sulfadimethoxine N4-acetate; N-Acetylsulfadimethoxine; 4-Acetamido-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide; Acetyl Sulfadimethoxine; Sulfadimethoxine Impurity C (Acetyl)
EINECS	Contact for details

Quality Control

Our N(4)-Acetylsulfadimethoxine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.