Description

(1R)-1α-Hydroxy-6,6,9Aβ-Trimethyl-4,5,5Aα,6,7,8,9,9A-Octahydronaphtho[1,2-C]Furan-3(1H)-One is a high-purity, chiral organic compound with a complex fused-ring structure. This molecule serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex bioactive molecules. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical sectors, where precise stereochemistry and purity are paramount for efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development and production of novel therapeutic agents, particularly in steroid-like or complex natural product-derived drug candidates.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its complex molecular framework for biological activity.
• Fine Chemical Production: Serves as a sophisticated building block in custom synthesis and contract manufacturing for high-value specialty chemicals.
• Research & Development: A valuable compound for academic and industrial R&D in organic chemistry, medicinal chemistry, and process development.
• Catalyst and Ligand Development: Potential use in the synthesis of chiral catalysts or ligands for asymmetric synthesis applications.

Basic Information

Product Name	(1R)-1α-Hydroxy-6,6,9Aβ-Trimethyl-4,5,5Aα,6,7,8,9,9A-Octahydronaphtho[1,2-C]Furan-3(1H)-One
CAS No.	24173-70-4
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	(1R)-1α-Hydroxy-6,6,9aβ-trimethyl-4,5,5aα,6,7,8,9,9a-octahydronaphtho[1,2-c]furan-3(1H)-one; (1R,5aR,9aS)-1-Hydroxy-6,6,9a-trimethyl-1,4,5,5a,6,7,8,9,9a-decahydronaphtho[1,2-c]furan-3-one; 1α-Hydroxy-6,6,9aβ-trimethyl-4,5,5aα,6,7,8,9,9a-octahydronaphtho[1,2-c]furan-3(1H)-one; (1R)-1α-Hydroxy-6,6,9aβ-trimethyl-4,5,5aα,6,7,8,9,9a-octahydronaphtho[1,2-c]furan-3(1H)-one; 24173-70-4; Octahydronaphthofuranone derivative.
EINECS	Contact for details

Quality Control

Our (1R)-1α-Hydroxy-6,6,9Aβ-Trimethyl-4,5,5Aα,6,7,8,9,9A-Octahydronaphtho[1,2-C]Furan-3(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, chiral analysis, and NMR, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.