Description

11α-Hydroxy-2,12β-Dimethoxypicras-2-Ene-1,16-Dione is a high-purity, specialized quassinoid derivative, a class of compounds known for their significant biological activity. This compound is valued for its role as a critical intermediate and reference standard in advanced pharmaceutical and biochemical research. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and phytochemical sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents, particularly in anti-cancer and anti-parasitic research.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate cellular pathways and enzyme interactions.
• Natural Product Chemistry: Acts as a pure analytical standard for the isolation, identification, and quantification of quassinoids in plant extracts.
• Academic Research: Employed in university and institutional labs for fundamental studies on the structure-activity relationships of terpenoid compounds.
• High-Throughput Screening (HTS): Utilized in compound libraries for screening against various biological targets to identify potential lead molecules.

Basic Information

Product Name	11α-Hydroxy-2,12β-Dimethoxypicras-2-Ene-1,16-Dione
CAS No.	24148-77-4
Molecular Formula	C22H28O7
Molecular Weight	404.46 g/mol
Synonyms	Picras-2-ene-1,16-dione, 11α-hydroxy-2,12β-dimethoxy-; 11α-Hydroxy-2,12β-dimethoxypicras-2-ene-1,16-dione; 2,12β-Dimethoxy-11α-hydroxypicras-2-ene-1,16-dione; Ailanthone derivative; Quassinoid derivative; (2S,5aS,6R,8aS,9R,10aS,10bS)-6-Hydroxy-9-methoxy-2-((R)-1-methoxyethyl)-5a,7,8,8a,9,10,10a,10b-octahydro-2H-3,6a-ethenocyclohepta[cd]indene-1,4(6H)-dione
EINECS	Contact for details

Quality Control

Our 11α-Hydroxy-2,12β-Dimethoxypicras-2-Ene-1,16-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.