Description

4-Bromobutyrophenone is a versatile brominated aromatic ketone that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive bromine and carbonyl functional groups, enabling efficient carbon-carbon bond formation and molecular diversification. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active compounds and materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl ketone or phenethylamine backbones.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating advanced organic electronic materials and display components.
• Organic Synthesis Reagent: Employed in Friedel-Crafts acylation, Grignard reactions, and nucleophilic substitution reactions to introduce the butyrophenone moiety.
• Chemical Research & Development: A valuable tool for medicinal chemists and material scientists in structure-activity relationship (SAR) studies and novel compound library generation.
• Fine Chemical Manufacturing: Intermediate for producing flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	4-Bromobutyrophenone
CAS No.	24070-52-8
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	1-(4-Bromophenyl)-1-butanone; p-Bromobutyrophenone; 4'-Bromobutyrophenone; Butyrophenone, 4'-bromo-; ω-Bromo-4-butyrophenone; 4-Bromophenyl propyl ketone; (4-Bromophenyl) propyl ketone; NSC 404087
EINECS	Contact for details

Quality Control

Our 4-Bromobutyrophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.