Description

2,5-Dihydro-5-[4-(trifluoromethyl)phenyl]-3H-imidazo[2,1-a]isoindol-5-ol is a high-value, complex heterocyclic compound featuring a fused imidazo-isoindole core substituted with a trifluoromethylphenyl group. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, drug-like heterocyclic structure.
• Agrochemical Development: Acts as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the imidazo-isoindole core.
• Organic Synthesis Reagent: Employed in advanced organic synthesis for constructing complex polycyclic frameworks in academic and industrial laboratories.
• Material Science Precursor: Investigated for use in the development of specialty polymers or organic electronic materials where fluorinated aromatic systems are advantageous.

Basic Information

Item	Details
Product Name	2,5-Dihydro-5-[4-(trifluoromethyl)phenyl]-3H-imidazo[2,1-a]isoindol-5-ol
CAS No.	24033-18-9
Molecular Formula	C17H11F3N2O
Molecular Weight	316.28 g/mol
Synonyms	5-[4-(Trifluoromethyl)phenyl]-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol; 3H-Imidazo[2,1-a]isoindol-5-ol, 2,5-dihydro-5-[4-(trifluoromethyl)phenyl]-; 24033-18-9; 5-(4-(Trifluoromethyl)phenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol; Imidazo[2,1-a]isoindole derivative; Trifluoromethylphenyl-substituted imidazoisoindole
EINECS	Contact for details

Quality Control

Our 2,5-Dihydro-5-[4-(trifluoromethyl)phenyl]-3H-imidazo[2,1-a]isoindol-5-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.