Description

1-(3-Chlorophenyl)-4,4,4-Trifluorobutane-1,3-Dione is a versatile fluorinated β-diketone building block. This compound is valued for its unique chemical structure, which combines a chlorophenyl group with a trifluoromethyl-substituted diketone moiety, making it a critical intermediate in advanced synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients, as well as by specialty chemical manufacturers for developing advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Advanced Material Research: Employed in the synthesis of fluorinated polymers and organic electronic materials, contributing to properties like thermal stability and solubility.
• Chemical Research & Development: A valuable building block for exploring new organic reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Product Name	1-(3-Chlorophenyl)-4,4,4-Trifluorobutane-1,3-Dione
CAS No.	23975-61-3
Molecular Formula	C10H6ClF3O2
Molecular Weight	250.60 g/mol
Synonyms	3'-Chloro-4,4,4-trifluoro-1-phenylbutane-1,3-dione; 3-Chlorophenyl Trifluoroacetylacetone; 1-(3-Chlorophenyl)-4,4,4-trifluoro-1,3-butanedione; 3'-Chloro-α,α,α-trifluoroacetophenone; 4,4,4-Trifluoro-1-(3-chlorophenyl)-1,3-butanedione; 3-Chloro-α,α,α-trifluoroacetophenone; 1-(3-Chlorophenyl)-4,4,4-trifluoroacetylacetone
EINECS	Contact for details

Quality Control

Our 1-(3-Chlorophenyl)-4,4,4-Trifluorobutane-1,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.