Description

2-Bromo-1-(2-Chloropyridin-4-Yl)Ethanone is a high-purity halogenated pyridinyl ketone building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional reactivity, serving as a versatile electrophilic synthon for constructing complex heterocyclic scaffolds and pharmaceutical intermediates. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex pyridine and fused heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require halogenated pyridine motifs.
• Chemical Biology Probe Development: Serves as a reactive handle for the functionalization of biomolecules and the creation of targeted covalent inhibitors in drug discovery.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	2-Bromo-1-(2-Chloropyridin-4-Yl)Ethanone
CAS No.	23794-16-3
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	2-Bromo-1-(2-chloro-4-pyridinyl)ethanone; 2-Bromo-2'-chloro-4'-pyridyl methyl ketone; 4-Acetyl-2-chloropyridine, 2-bromo derivative; 2-Chloro-4-pyridyl bromomethyl ketone; 1-(2-Chloro-4-pyridinyl)-2-bromoethanone; α-Bromo-2-chloroisonicotinoyl methyl ketone; Ethanone, 2-bromo-1-(2-chloro-4-pyridinyl)-; Bromo(2-chloropyridin-4-yl)methyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(2-Chloropyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.