Description

2,2-Dimethyl-4(R)-4-Iodomethyl-1,3-Dioxalane is a high-value chiral building block and versatile synthetic intermediate. Its core value proposition lies in its reactive iodomethyl group and protected diol functionality, enabling precise stereochemistry in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical sectors, particularly for the synthesis of active pharmaceutical ingredients (APIs), nucleoside analogs, and other specialty organic molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of antiviral, anticancer, and other therapeutic agents.
• Nucleoside Chemistry: Used in the preparation of modified nucleosides and nucleotides for drug discovery and biochemical research.
• Asymmetric Synthesis: Serves as a precursor for introducing chiral centers in complex natural products and fine chemicals.
• Polymer Science: Potential monomer or cross-linking agent for creating functional polymers with specific properties.
• Ligand and Catalyst Development: Building block for synthesizing novel chiral ligands and organocatalysts.
• Agrochemical Research: Intermediate in the development of advanced, stereochemically defined crop protection agents.

Basic Information

Product Name	2,2-Dimethyl-4(R)-4-Iodomethyl-1,3-Dioxalane
CAS No.	23735-39-9
Molecular Formula	C6H11IO2
Molecular Weight	242.06 g/mol
Synonyms	(R)-2,2-Dimethyl-4-iodomethyl-1,3-dioxolane; (4R)-2,2-Dimethyl-4-(iodomethyl)-1,3-dioxolane; 4(R)-Iodomethyl-2,2-dimethyl-1,3-dioxolane; (R)-4-Iodomethyl-2,2-dimethyl-1,3-dioxolane; D-(-)-2,2-Dimethyl-4-iodomethyl-1,3-dioxolane; (R)-(-)-2,2-Dimethyl-4-iodomethyl-1,3-dioxolane; Chiral iodomethyl dioxolane; Acetonide protected iodohydrin derivative
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4(R)-4-Iodomethyl-1,3-Dioxalane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.