Description

Dl-Erythro-Methylphenidate Hydrochloride CAS NO 23644-60-2 is a synthetic stimulant compound of significant pharmaceutical interest. It serves as a key intermediate and reference standard in the research and development of central nervous system (CNS) active agents. This material is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers of active pharmaceutical ingredients (APIs). Its precise stereochemistry makes it valuable for comparative studies and method development.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control testing in drug manufacturing.
• Research Chemical Intermediate: Serves as a critical building block in the synthesis of novel CNS-targeting compounds and for metabolic pathway studies.
• Analytical Chemistry: Employed as a calibrant or control in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and spectroscopic analyses.
• Pharmacological Research: Utilized in *in-vitro* and preclinical studies to investigate stimulant activity, receptor binding, and pharmacokinetic properties.
• Impurity Profiling: Acts as a known impurity or related substance standard for the characterization of pharmaceutical products.
• Educational & Forensic Analysis: Used in academic settings for advanced chemistry education and in forensic laboratories for identification purposes.

Basic Information

Product Name	Dl-Erythro-Methylphenidate Hydrochloride
CAS No.	23644-60-2
Molecular Formula	C14H19NO2·HCl
Molecular Weight	269.77 g/mol (Free base: 233.31 g/mol)
Synonyms	DL-erythro-Methylphenidate HCl; (±)-erythro-Methylphenidate Hydrochloride; Methyl α-phenyl-2-piperidineacetate hydrochloride (racemic erythro); Ritatin (intermediate form); MPH HCl; DL-three-Methylphenidate Hydrochloride isomer; α-Phenyl-2-piperidineacetic acid methyl ester hydrochloride; Methylphenidate Hydrochloride (DL, erythro racemate)
EINECS	Contact for details

Quality Control

Our Dl-Erythro-Methylphenidate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) detailing specifications such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable and traceable material for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Chiral Purity (HPLC)	DL-erythro isomer: ≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.