Description

1-(4-Aminophenyl)-2,2,2-Trifluoro-1-Ethanone is a high-purity aromatic trifluoromethyl ketone derivative featuring both an amine and a ketone functional group. This unique bifunctional structure makes it a versatile and critical building block for advanced organic synthesis, particularly in the development of complex molecules. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical R&D teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing trifluoromethyl groups which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-withdrawing properties.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoroacetyl and aniline motifs into more complex molecular architectures in medicinal and process chemistry.

Basic Information

Product Name	1-(4-Aminophenyl)-2,2,2-Trifluoro-1-Ethanone
CAS No.	23516-79-2
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	4-Amino-α,α,α-trifluoroacetophenone; 4-Aminophenyl Trifluoromethyl Ketone; 1-(4-Aminophenyl)-2,2,2-trifluoroethanone; p-Amino-α,α,α-trifluoroacetophenone; 4-Trifluoroacetylaniline; 4-Amino-α,α,α-trifluoroacetophenone; 4'-Amino-2,2,2-trifluoroacetophenone; 23516-79-2
EINECS	Contact for details

Quality Control

Our 1-(4-Aminophenyl)-2,2,2-Trifluoro-1-Ethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.