Description

Tolypomycin Y CAS NO 23412-26-2 is a macrocyclic lactone antibiotic belonging to the tolypomycin family, known for its potent activity against Gram-positive bacteria. This compound is of significant interest in pharmaceutical research and development, particularly for studying novel antibacterial mechanisms and resistance profiles. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in antibiotic discovery, microbiology, and biochemical studies.

Application

• Antibacterial Research: Used as a reference standard and active agent in studies targeting Gram-positive pathogens.
• Mechanism of Action Studies: Investigation of bacterial RNA polymerase inhibition and related biochemical pathways.
• Microbiology Assays: Employed in in vitro susceptibility testing and antimicrobial activity screening.
• Pharmaceutical Development: Serves as a lead compound or intermediate in the synthesis and development of new antibiotic derivatives.
• Biochemical Research: Tool compound for exploring protein synthesis inhibition and cellular processes in prokaryotes.
• Quality Control: Acts as a certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	Tolypomycin Y
CAS No.	23412-26-2
Molecular Formula	C₄₃H₅₅NO₁₄
Molecular Weight	809.90 g/mol
Synonyms	Tolypomycin Y; Antibiotic Bu 2313; Bu-2313; Antibiotic Bu2313; NSC 163500; 5,6,7,8-Tetradehydro-8,16-dihydro-4-hydroxy-3,11-dimethoxy-8-methyl-10-[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxacyclohexadeca-5,12,14-triene-2,13-dione; (8S,10R,16R)-8,16-Dihydro-4-hydroxy-3,11-dimethoxy-8-methyl-10-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxacyclohexadeca-5,12,14-triene-2,13-dione
EINECS	Contact for details

Quality Control

Our Tolypomycin Y is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.