Description

5-Chloro-2-Iodotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chlorine and iodine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in cross-coupling reactions and the development of active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a monomer or building block for the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments.

Basic Information

Product Name	5-Chloro-2-Iodotoluene
CAS No.	23399-70-4
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	2-Iodo-5-chlorotoluene; 1-Chloro-4-iodo-2-methylbenzene; 5-Chloro-2-iodo-1-methylbenzene; 2-Methyl-5-chloroiodobenzene; 4-Chloro-2-iodotoluene; 2-Iodo-5-chloro-1-methylbenzene; Toluene, 5-chloro-2-iodo-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Iodotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.