Description

Methanesulfonamide, 1,1,1-Trifluoro-n-(2-Fluorophenyl)- is a specialized fluorinated sulfonamide derivative, serving as a critical high-value building block in advanced organic synthesis. Its unique structure, featuring both trifluoromethyl and fluorophenyl groups, makes it a versatile intermediate for introducing fluorine atoms and sulfonamide functionalities into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the sulfonamide and fluorine groups contribute to biological activity.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with specific thermal, chemical, or surface properties.
• Chemical Synthesis: Serves as a versatile reagent for introducing the N-(2-fluorophenyl)methanesulfonamide scaffold into more complex molecular architectures.
• Life Science Research: Employed in biochemical and pharmacological research as a tool compound for probing enzyme interactions or biological pathways.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-(2-Fluorophenyl)-
CAS No.	23383-98-4
Molecular Formula	C8H6F4NO2S
Molecular Weight	256.20 g/mol
Synonyms	N-(2-Fluorophenyl)-1,1,1-trifluoromethanesulfonamide; 1,1,1-Trifluoro-N-(2-fluorophenyl)methanesulfonamide; 2-Fluoro-N-(trifluoromethylsulfonyl)aniline; α,α,α-Trifluoro-N-(2-fluorophenyl)methanesulfonamide; N-(2-Fluorophenyl)trifluoromethanesulfonamide; Trifluoromethanesulfonanilide, 2-fluoro-; CAS 23383-98-4
EINECS	Contact for details

Quality Control

Every batch of our Methanesulfonamide, 1,1,1-Trifluoro-n-(2-Fluorophenyl)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality management system supports the stringent requirements of research and development applications, ensuring reliable performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.