Description

2,3:5,6-Di-o-Isopropylidene-D-Talono-1,4-Lactone is a high-purity, protected sugar lactone derivative, serving as a critical chiral building block and synthetic intermediate. Its locked bicyclic structure provides exceptional stereochemical control, making it invaluable for the synthesis of complex, biologically active molecules. This compound is essential for research and production in the pharmaceutical, fine chemical, and advanced material sectors, where precise chirality and functional group manipulation are paramount.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of complex carbohydrates, glycoconjugates, and specialty chemicals requiring defined stereochemistry.
• Asymmetric Catalysis: Employed as a chiral auxiliary or ligand precursor in enantioselective synthesis.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and glycoscience research.
• Material Science: Potential monomer for creating novel polymers with specific optical or structural properties.

Basic Information

Product Name	2,3:5,6-Di-o-Isopropylidene-D-Talono-1,4-Lactone
CAS No.	23262-80-8
Molecular Formula	C12H18O6
Molecular Weight	258.27 g/mol
Synonyms	2,3:5,6-Di-O-isopropylidene-D-talono-1,4-lactone; D-Talono-1,4-lactone 2,3:5,6-di-O-isopropylidene; 1,4-Lactone of 2,3:5,6-di-O-isopropylidene-D-talonic acid; Diacetone D-talonolactone; Di-O-isopropylidene-D-talono-1,4-lactone; 2,3:5,6-Di-O-(1-methylethylidene)-D-talono-1,4-lactone; D-Talono-γ-lactone 2,3:5,6-diisopropylidene acetal
EINECS	Contact for details

Quality Control

Our 2,3:5,6-Di-o-Isopropylidene-D-Talono-1,4-Lactone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.