Description

Acetonylmalonic Acid Diethyl Ester is a versatile organic ester building block, also known as Diethyl 3-oxoglutarate. This compound is valued for its reactive keto and ester functional groups, making it a crucial intermediate in multi-step organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds and complex carboxylic acid derivatives.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific keto-ester functionalities.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and specialty polymers where controlled reactivity is essential.
• Academic & Industrial Research: Employed in method development and as a starting material for novel compound libraries in medicinal chemistry.
• Chemical Synthesis: Utilized in Claisen condensation and other carbon-carbon bond-forming reactions to create complex, polyfunctional molecules.

Basic Information

Product Name	Acetonylmalonic Acid Diethyl Ester
CAS No.	23193-18-2
Molecular Formula	C9H14O5
Molecular Weight	202.20 g/mol
Synonyms	Diethyl 3-oxoglutarate; Diethyl 2-acetonylmalonate; 3-Oxoglutaric Acid Diethyl Ester; Acetonylmalonic Acid Diethyl Ester; Diethyl Acetonylmalonate; 1,5-Diethoxy-1,5-dioxopentan-3-one; Ethyl 3-oxoglutarate; 3-Oxopentanedioic Acid Diethyl Ester
EINECS	245-473-6

Quality Control

Our Acetonylmalonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.