Description

Virginiamycin S1 CAS NO 23152-29-6 is a specific component of the virginiamycin complex, a streptogramin antibiotic produced by *Streptomyces virginiae*. This compound is valued for its potent antibacterial activity, particularly against Gram-positive bacteria, and serves as a critical reference standard and active pharmaceutical ingredient. It is essential for researchers, pharmaceutical manufacturers, and quality control laboratories involved in antimicrobial development and analysis. The product is supplied with a focus on high purity and reliable consistency to meet stringent research and production requirements.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of virginiamycin in pharmacopeial methods (e.g., USP, EP).
• Antimicrobial Research: Serves as a key tool in microbiological studies, mechanism of action investigations, and the development of new streptogramin-based antibiotics.
• Veterinary Pharmaceutical Ingredient: Employed in the formulation of growth promoters and therapeutic agents for livestock, targeting Gram-positive infections.
• Microbiological Assay Development: Utilized to calibrate bioassay systems and validate methods for antibiotic potency determination.
• Quality Control & Stability Testing: Acts as a benchmark in impurity profiling and stability-indicating methods for antibiotic manufacturing.
• Biochemical Research: Applied in studies of bacterial protein synthesis inhibition and ribosomal function.

Basic Information

Product Name	Virginiamycin S1
CAS No.	23152-29-6
Molecular Formula	C43H49N7O10
Molecular Weight	823.90 g/mol
Synonyms	Virginiamycin S1; Antibiotic PA 114 S1; Mikamycin S1; Staphylomycin S1; Streptogramin A; Pristinamycin IIA; Vernamycin A; Antibiotic 899 S1; (3R,4S,5S,6R,8R,11S,12E,14E)-11-[[(2S,3R,4R)-3,4-Dimethyl-1-oxo-2-(1-oxopropyl)azetidin-4-yl]thio]-5,6,8,15-tetrahydro-3-methoxy-5,6,8,10,12,14-hexamethyl-15-oxo-9H-3,13-(epoxypentadeca-1,11-dienimino)benz[d]indolizine-4-carboxylic acid methyl ester
EINECS	245-455-6

Quality Control

Our Virginiamycin S1 is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and MS, and determination of related substances. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all test results against established specifications. The product is suitable for use as a pharmaceutical reference standard and in GLP/GMP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.