Description

Bruceine F is a bioactive quassinoid compound isolated from the Brucea javanica plant, recognized for its significant pharmacological potential. This high-purity standard is essential for research and development in the pharmaceutical and nutraceutical sectors, where precise chemical characterization is critical. It serves as a key reference material for scientists and quality control professionals working on anti-inflammatory, anti-tumor, and antiparasitic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of herbal extracts and finished products in quality control laboratories.
• Bioactivity Research: Serves as a lead compound in pharmacological studies investigating anti-cancer, anti-malarial, and anti-inflammatory mechanisms of action.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the standardization and fingerprint analysis of Brucea javanica (Ya Dan Zi) extracts in TCM and botanical supplements.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research into quassinoid chemistry, biosynthesis, and structure-activity relationships (SAR).
• Preclinical Development: Employed in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and toxicology profiles for potential new drug candidates.

Basic Information

Product Name	Bruceine F
CAS No.	23112-07-4
Molecular Formula	C20H28O9
Molecular Weight	412.43 g/mol
Synonyms	Bruceine F; (1R,2S,12bS)-1,2,12-Trimethoxy-6-[(2R,3S,4R,5S)-3,4,5-trimethoxyoxan-2-yl]oxy-4a,7,8,13-tetrahydro-1H-picene-3,11-dione; 6-[(3,4,5-Trimethoxy-6-oxanyl)oxy]-1,2,12-trimethoxy-4a,7,8,13-tetrahydro-1H-picene-3,11-dione; Ailanthone analog; Quassinoid
EINECS	Contact for details

Quality Control

Every batch of Bruceine F is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full traceability and detailed chromatographic data (HPLC, LC-MS) for each specific lot.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.