Description

Bicyclo[3.2.1]Octa-3,6-Diene-2-Carboxylic Acid (8Ci) is a specialized bicyclic, unsaturated carboxylic acid building block of significant interest in advanced organic synthesis. Its unique strained ring structure and conjugated diene system make it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical and material science research. This high-purity intermediate is essential for chemists developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional polymers where precise stereochemistry and reactivity are critical.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its rigid bicyclic framework.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions and other cycloadditions to create complex polycyclic compounds for academic and industrial R&D.
• Flavor & Fragrance Chemistry: Utilized as a starting material for synthesizing unique terpenoid-like aroma molecules.
• Catalyst Ligand Precursor: Provides a scaffold for developing novel chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	Bicyclo[3.2.1]Octa-3,6-Diene-2-Carboxylic Acid (8Ci)
CAS No.	23085-05-4
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	Bicyclo[3.2.1]octa-3,6-diene-2-carboxylic acid; 2-Bicyclo[3.2.1]octa-3,6-dienecarboxylic acid; 8CI; NSC 163063; 2-Norbornene-2-carboxylic acid (derivative); 3,6-Dihydrobicyclo[3.2.1]oct-3-ene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Bicyclo[3.2.1]Octa-3,6-Diene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.