Description

1-Butanone, 2-Fluoro-1-Phenyl- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a reactive ketone group with a fluorine substituent and an aromatic ring, enabling precise chemical modifications. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic ketone motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence profiles.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic components.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via reactions at the ketone carbonyl or through functionalization of the aromatic ring.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the electronic and steric effects of fluorine substitution adjacent to a carbonyl group in aromatic systems.

Basic Information

Product Name	1-Butanone, 2-Fluoro-1-Phenyl- (9Ci)
CAS No.	23071-44-5
Molecular Formula	C₁₀H₁₁FO
Molecular Weight	166.19 g/mol
Synonyms	2-Fluoro-1-phenylbutan-1-one; 2-Fluoro-1-phenyl-1-butanone; α-Fluorobutyrophenone; 1-Phenyl-2-fluorobutan-1-one; Butyrophenone, 2-fluoro-; 2-Fluorobutyrophenone; NSC 403119; 2-Fluoro-1-phenylbutanone
EINECS	Contact for details

Quality Control

Our 1-Butanone, 2-Fluoro-1-Phenyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.