Description

(2E)-1,3-Bis(4-Chlorophenyl)-2-Propene-1-One is a high-purity, diaryl-substituted propenone derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its defined stereochemistry and reactive α,β-unsaturated ketone moiety, enabling precise construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its chlorinated aromatic structure.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Organic Synthesis: Serves as a versatile Michael acceptor or a precursor for heterocyclic compounds like pyrazoles and isoxazoles in fine chemical production.
• Chemical Biology: Utilized as a probe or scaffold in the study of biological pathways and protein interactions.

Basic Information

Product Name	(2E)-1,3-Bis(4-Chlorophenyl)-2-Propene-1-One
CAS No.	22966-30-9
Molecular Formula	C15H10Cl2O
Molecular Weight	277.15 g/mol
Synonyms	(E)-1,3-Bis(4-chlorophenyl)prop-2-en-1-one; (E)-1,3-Di(4-chlorophenyl)-2-propen-1-one; (E)-4,4'-Dichlorochalcone; 4,4'-Dichlorochalcone; (E)-3-(4-Chlorophenyl)-1-(4-chlorophenyl)prop-2-en-1-one; Chalcone, 4,4'-dichloro-; NSC 403697; 2-Propen-1-one, 1,3-bis(4-chlorophenyl)-, (2E)-
EINECS	Contact for details

Quality Control

Our (2E)-1,3-Bis(4-Chlorophenyl)-2-Propene-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.