Description

(E)-1-(4-Bromophenyl)-3-Phenyl-2-Propene-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a versatile and critical organic intermediate for advanced chemical synthesis, offering a reactive scaffold for constructing more complex molecular architectures. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and academic research institutions engaged in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for anti-inflammatory, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its chalcone backbone.
• Material Science Research: Serves as a precursor for organic semiconductors, non-linear optical (NLO) materials, and advanced polymers.
• Medicinal Chemistry: A crucial scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology: Employed as a probe or inhibitor in biochemical assays to study enzyme interactions and pathways.
• Academic & Industrial R&D: Fundamental research reagent for organic synthesis methodologies, including cyclization and coupling reactions.

Basic Information

Product Name	(E)-1-(4-Bromophenyl)-3-Phenyl-2-Propene-1-One
CAS No.	22966-23-0
Molecular Formula	C15H11BrO
Molecular Weight	287.15 g/mol
Synonyms	(E)-4-Bromochalcone; 4'-Bromochalcone; 1-(4-Bromophenyl)-3-phenyl-2-propen-1-one; 3-(4-Bromophenyl)-1-phenyl-2-propen-1-one; (E)-1-(4-Bromophenyl)-3-phenylprop-2-en-1-one; p-Bromochalcone; 2-Propen-1-one, 1-(4-bromophenyl)-3-phenyl-, (E)-; NSC 403697
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Bromophenyl)-3-Phenyl-2-Propene-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with the standards expected for research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.