Description

2-[(E)-1-Propenyl]-1,3,2-Dioxaborolane is a versatile organoboron reagent, specifically a protected boronic ester derivative of trans-1-propenylboronic acid. This compound matters as a critical building block in modern synthetic chemistry, enabling precise carbon-carbon bond formation through cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the trans-1-propenyl group into aromatic and heteroaromatic systems to create advanced intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs) and drug candidates requiring specific alkene geometries.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the propenyl moiety is a key structural feature.
• Material Science & OLED Research: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and light-emitting materials.
• Organic Synthesis & Methodology Development: A valuable tool for academic and industrial research in developing new catalytic cycles and synthetic transformations.
• Fine Chemical Manufacturing: Used in the multi-step synthesis of complex flavors, fragrances, and specialty chemicals.

Basic Information

Product Name	2-[(E)-1-Propenyl]-1,3,2-Dioxaborolane
CAS No.	22885-64-9
Molecular Formula	C7H13BO2
Molecular Weight	139.99 g/mol
Synonyms	(E)-1-Propenylboronic Acid Pinacol Ester; trans-1-Propenylboronic Acid Pinacol Ester; 4,4,5,5-Tetramethyl-2-[(E)-prop-1-en-1-yl]-1,3,2-dioxaborolane; 2-[(1E)-1-Propen-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-1-Propenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; trans-Propenyl Pinacol Boronate; (E)-1-PropenylBpin
EINECS	Contact for details

Quality Control

Our 2-[(E)-1-Propenyl]-1,3,2-Dioxaborolane is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (¹H, ¹¹B, ¹³C), GC/HPLC for purity, and color/clarity assessment, to ensure it meets the high standards required for sensitive cross-coupling chemistry. Certificates of Analysis (COA) with full analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept under an inert atmosphere (nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (E/Z ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.