Description

4,4'-Bis(Trifluoromethyl)Benzhydrol is a high-value fluorinated organic intermediate characterized by its benzhydrol core flanked by two trifluoromethyl groups. This molecular structure is critical for imparting enhanced lipophilicity, metabolic stability, and unique electronic properties to advanced materials and pharmaceuticals. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, where the trifluoromethyl groups improve blood-brain barrier penetration.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its stability and bioactivity to create more effective and selective crop protection agents.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays, where it contributes to improved thermal stability, lower viscosity, and enhanced optical properties.
• Advanced Polymer Monomer: Incorporated into specialty polymers, such as polyimides and epoxy resins, to increase chemical resistance, lower dielectric constants, and enhance thermal performance for high-tech coatings and electronics.
• Ligand & Catalyst Development: Utilized in organometallic chemistry and catalysis research to create sophisticated ligands that modulate metal center reactivity for more efficient synthetic processes.

Basic Information

Product Name	4,4'-Bis(Trifluoromethyl)Benzhydrol
CAS No.	22543-52-8
Molecular Formula	C₁₅H₁₀F₆O
Molecular Weight	320.23 g/mol
Synonyms	Bis(4-(trifluoromethyl)phenyl)methanol; α,α-Bis[4-(trifluoromethyl)phenyl]methanol; (4-(Trifluoromethyl)phenyl)(4-(trifluoromethyl)phenyl)methanol; 4,4'-(Hydroxymethylene)bis(trifluoromethylbenzene); 4,4'-Bis(trifluoromethyl)benzhydrol; 1,1'-(Hydroxymethylene)bis[4-(trifluoromethyl)benzene]; 4,4'-(Trifluoromethyl)benzhydrol
EINECS	Contact for details

Quality Control

Every batch of 4,4'-Bis(Trifluoromethyl)Benzhydrol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.