Description

1,2-o-Isopropylidene-3-Benzyloxy-D-Glucofuranose is a key protected carbohydrate intermediate, specifically a benzyl-protected derivative of isopropylidene glucose. This compound is critically important for its role in the stereoselective synthesis of complex sugars, nucleosides, and other bioactive molecules, where it serves as a versatile chiral building block. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of nucleoside analogs, antiviral drugs, and other therapeutic agents.
• Glycochemistry Research: Used in the preparation of complex oligosaccharides, glycoconjugates, and glycomimetics for biological studies.
• Agrochemical Synthesis: Serves as a starting material for creating chiral active ingredients with specific biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Academic & R&D Laboratories: A standard reagent for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	1,2-o-Isopropylidene-3-Benzyloxy-D-Glucofuranose
CAS No.	22529-61-9
Molecular Formula	C₁₆H₂₂O₆
Molecular Weight	310.34 g/mol
Synonyms	3-O-Benzyl-1,2-O-isopropylidene-α-D-glucofuranose; 3-O-Benzyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (common misnomer); 1,2-O-Isopropylidene-3-O-benzyl-α-D-glucofuranose; 3-Benzyloxy-1,2-O-isopropylidene-α-D-glucofuranose; D-Glucofuranose, 3-(benzyloxy)-1,2-O-(1-methylethylidene)-; Benzyl 3-O-(1,2-O-isopropylidene-α-D-glucofuranosyl) ether; Protected D-Glucose Benzyl Ether
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-3-Benzyloxy-D-Glucofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-30° to -35° (c=1 in CHCl₃)
Melting Point	95°C - 100°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.