Description

6,6-Diphenylbicyclo[3.1.0]Hexan-2-One is a specialized bicyclic ketone compound featuring a unique strained ring system. This structure makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in synthetic organic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing complex stereochemistry.
• Agrochemical Synthesis: Serves as a key building block for developing new generation herbicides, fungicides, and insecticides with unique modes of action.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and performance materials where its rigid, polycyclic framework imparts specific properties.
• Academic & Industrial R&D: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Ligand and Catalyst Development: The diphenyl-substituted bicyclic structure can be functionalized to create novel chiral ligands or organocatalysts for asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with enhanced thermal stability or specific optical properties.

Basic Information

Item	Details
Product Name	6,6-Diphenylbicyclo[3.1.0]Hexan-2-One
CAS No.	22524-16-9
Molecular Formula	C19H18O
Molecular Weight	262.35 g/mol
Synonyms	6,6-Diphenylbicyclo[3.1.0]hexan-2-one; 2-Bicyclo[3.1.0]hexanone, 6,6-diphenyl-; 6,6-Diphenyl-2-bicyclo[3.1.0]hexanone; 6,6-Diphenylbicyclo[3.1.0]hexanone; 6,6-Diphenyl-2-norcarano
EINECS	Contact for details

Quality Control

Our production of 6,6-Diphenylbicyclo[3.1.0]Hexan-2-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for critical R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical intermediate use, and we welcome audits and specific quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.