Description

Gymnemagenin CAS NO 22467-07-8 is a bioactive triterpenoid saponin aglycone derived from the leaves of the *Gymnema sylvestre* plant. This compound is of significant commercial interest due to its role as the primary sapogenin responsible for the characteristic taste-modifying and anti-sweet properties associated with Gymnema extracts. It serves as a critical reference standard and active pharmaceutical ingredient (API) for manufacturers in the nutraceutical, pharmaceutical, and research sectors focused on metabolic health and natural product development.

Application

• Pharmaceutical Intermediates: Serves as a key starting material or reference standard for the synthesis and quality control of Gymnema-based pharmaceutical formulations.
• Dietary Supplements & Nutraceuticals: Used as a standardized active ingredient in capsules, tablets, and powders aimed at supporting healthy blood sugar metabolism and weight management.
• Clinical & Biomedical Research: Employed as a pure biochemical tool in *in vitro* and *in vivo* studies investigating mechanisms related to glucose absorption, pancreatic function, and sweet taste perception.
• Reference Standard for QC/QA: Essential for HPLC and LC-MS analysis to authenticate and quantify Gymnema extracts, ensuring product potency and consistency for finished goods manufacturers.
• Functional Food & Beverage Development: Incorporated into specialized food products designed for glycemic control and sugar-craving management.
• Cosmeceutical Ingredients: Explored for use in topical formulations targeting skin health due to its triterpenoid structure and potential bioactive properties.

Basic Information

Product Name	Gymnemagenin
CAS No.	22467-07-8
Molecular Formula	C30H46O6
Molecular Weight	502.69 g/mol
Synonyms	Gymnemagenin; (3β,4β,16β,21β,22α)-21,22-Dihydroxy-16,28-epoxyolean-12-en-3-yl β-D-glucopyranosiduronic acid aglycone; Gymnemic acid aglycone; Gymnemic acid IV aglycone; Gymnemic acid I aglycone; Gymnema saponin aglycone; Gymnestrogenin
EINECS	Contact for details

Quality Control

Our Gymnemagenin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and commercial use. Quality is verified through comprehensive analytical testing including HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance requirements for cGMP, ISO, and other relevant quality systems upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.