Description

(1Ar)-1,1A,6,7,7A,7Bβ-Hexahydro-1,1,7β,7Aβ-Tetramethyl-5H-Cyclopropa[A]Naphthalen-5-One CAS NO 22391-34-0 is a complex, high-purity synthetic intermediate belonging to the class of polycyclic ketones. This compound is valued for its unique sterically hindered structure, which makes it a critical building block in advanced organic synthesis. It is primarily sought after by research and development laboratories and fine chemical manufacturers in the pharmaceutical and fragrance industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly for complex natural product analogs and steroidal frameworks.
• Fragrance & Flavor Chemistry: Used in the research and development of high-value aroma chemicals, contributing unique woody, amber, or musky olfactory notes due to its polycyclic structure.
• Advanced Material Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or optical properties.
• Agrochemical Synthesis: Employed in the creation of new active ingredients for crop protection, leveraging its complex hydrocarbon skeleton.
• Catalyst Ligand Development: Investigated as a backbone for designing novel chiral ligands used in asymmetric catalysis.
• Academic & Industrial R&D: Utilized in methodological studies and process chemistry for constructing challenging carbon-carbon bonds.

Basic Information

Product Name	(1Ar)-1,1A,6,7,7A,7Bβ-Hexahydro-1,1,7β,7Aβ-Tetramethyl-5H-Cyclopropa[A]Naphthalen-5-One
CAS No.	22391-34-0
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	1,1a,6,7,7a,7b-Hexahydro-1,1,7b,7a-tetramethyl-5H-cyclopropa[a]naphthalen-5-one; Ambroxide Precursor; 8,12-Epoxy-13,14,15,16-tetranorlabdane; Tetramethyl cyclopropanaphthalenone; (1aR,7aS,7bR)-1a,6,7,7a-Tetrahydro-1,1,7b,7a-tetramethyl-5H-cyclopropa[a]naphthalen-5-one; Ambroxan related intermediate; Dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan (related structure)
EINECS	Contact for details

Quality Control

Our (1Ar)-1,1A,6,7,7A,7Bβ-Hexahydro-1,1,7β,7Aβ-Tetramethyl-5H-Cyclopropa[A]Naphthalen-5-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.