Description

(3R,8Aα)-2,3,4,5,6,7,8,8A-Octahydro-7,7-Dimethyl-8-Methylene-1H-3Aα,6α-Methanoazulene-3β-Carboxylic Acid is a high-purity, functionalized methanoazulene derivative, a key chiral intermediate in advanced organic synthesis. Its complex, rigid bicyclic structure makes it a valuable building block for the development of novel pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create complex molecular architectures with specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Research: Used as a precursor in the development of new pesticides and herbicides, leveraging its unique carbon skeleton for bioactivity.
• Fragrance & Flavor Chemistry: Acts as a starting material for the synthesis of complex, high-value odorants and flavorants due to its terpene-related structure.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific optical or thermal properties.
• Academic & R&D: A valuable tool for methodological studies in organic synthesis, including catalysis, asymmetric synthesis, and natural product total synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex molecules for electronics, coatings, and other high-tech applications.

Basic Information

Product Name	(3R,8Aα)-2,3,4,5,6,7,8,8A-Octahydro-7,7-Dimethyl-8-Methylene-1H-3Aα,6α-Methanoazulene-3β-Carboxylic Acid
CAS No.	22387-77-5
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	3β-Carboxy-7,7-dimethyl-8-methylenebicyclo[5.3.0]decane; 3β-Carboxy-7,7-dimethyl-8-methylenebicyclo[5.3.0]decane; 8-Methylene-7,7-dimethylbicyclo[5.3.0]decane-3β-carboxylic acid; (1R,3aS,6aR)-1,2,3,3a,4,5,6,6a-Octahydro-4,4-dimethyl-7-methylenepentalene-1-carboxylic acid; 3β-Carboxy-7,7-dimethyl-8-methylenebicyclo[5.3.0]decane; A derivative of 2,3,4,5,6,7,8,8a-Octahydro-7,7-dimethyl-8-methylene-1H-3a,6-methanoazulene
EINECS	Contact for details

Quality Control

Our (3R,8Aα)-2,3,4,5,6,7,8,8A-Octahydro-7,7-Dimethyl-8-Methylene-1H-3Aα,6α-Methanoazulene-3β-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and NMR/IR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.