Description

Difluoro-Phenylsulfanyl-Acetic Acid Methyl Ester is a specialized fluorinated building block featuring a phenylsulfanyl (thioether) linkage and an ester functional group. This compound is valued for its unique molecular architecture, which enables the introduction of both fluorine atoms and a sulfur-containing moiety into target molecules, significantly altering their physicochemical and biological properties. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where the difluoro and thioether groups enhance bioavailability and activity.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers, coatings, or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biochemical pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	Difluoro-Phenylsulfanyl-Acetic Acid Methyl Ester
CAS No.	22340-44-9
Molecular Formula	C9H8F2O2S
Molecular Weight	218.22 g/mol
Synonyms	Methyl 2-(2,4-Difluorophenylthio)acetate; 2-((2,4-Difluorophenyl)thio)acetic acid methyl ester; Methyl (2,4-difluorophenylthio)acetate; Acetic acid, 2-((2,4-difluorophenyl)thio)-, methyl ester; Methyl 2,4-difluorophenylthioacetate; 2,4-Difluorophenylthioacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Difluoro-Phenylsulfanyl-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.