Description

Polygalacic Acid is a bioactive triterpenoid compound, also known as Polygalacic Acid CAS NO 22338-71-2, valued for its significant pharmacological and research applications. Its primary commercial importance lies in its role as a key reference standard and active pharmaceutical ingredient (API) intermediate for the development of anti-inflammatory and neuroprotective agents. This high-purity compound is essential for manufacturers and research institutions in the pharmaceutical, nutraceutical, and advanced life science sectors requiring consistent, well-characterized materials for product development and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and assay development of herbal medicines and botanical extracts.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents targeting inflammation and neurological disorders.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into high-end supplement products for its purported bioactive properties, requiring verified purity and potency.
• Biomedical & Pharmacological Research: Employed in in vitro and in vivo studies to investigate mechanisms of action, efficacy, and safety profiles.
• Cosmeceutical Development: Used in the research and formulation of advanced skincare products for its potential anti-inflammatory and skin-soothing benefits.
• Analytical Chemistry & Method Development: Essential for developing and validating analytical methods such as HPLC and LC-MS for the detection and quantification of triterpenoids in complex matrices.

Basic Information

Product Name	Polygalacic Acid
CAS No.	22338-71-2
Molecular Formula	C30H48O5
Molecular Weight	488.70 g/mol
Synonyms	2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid; 3-Epi-echinocystic acid; (2β,3β,16α)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid; Polygalacic acid; Echinocystic acid 3-epimer; Radix Polygalae Triterpenoid Saponin
EINECS	Contact for details

Quality Control

Our Polygalacic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, IR and MS for identification, and comprehensive residual solvent and heavy metal screening to ensure it meets high-grade specifications suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed-upon specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.