Description

(4S)-4α,5-Dihydroxytetralin-1-One CAS NO 22332-51-0 is a high-purity chiral tetralone derivative, a key synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and functional groups make it a valuable building block for the synthesis of complex molecules, particularly in pharmaceutical research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or intermediate in stereoselective synthesis to construct complex molecules with defined chirality.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its fused ring structure.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and advanced materials where specific stereochemistry is required.
• Academic & R&D Laboratories: Used in methodological research and the discovery of new synthetic pathways in organic and medicinal chemistry.
• Process Chemistry Development: Acts as a model compound for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(4S)-4α,5-Dihydroxytetralin-1-One
CAS No.	22332-51-0
Molecular Formula	C₁₀H₁₀O₃
Molecular Weight	178.18 g/mol
Synonyms	(4S)-4,5-Dihydroxy-3,4-dihydronaphthalen-1(2H)-one; (4S)-4,5-Dihydroxy-1-tetralone; (S)-4,5-Dihydroxy-α-tetralone; 1(2H)-Naphthalenone, 4,5-dihydroxy-3,4-dihydro-, (4S)-; (4S)-4,5-Dihydroxy-3,4-dihydro-1(2H)-naphthalenone; (S)-4,5-Dihydroxytetralone; 4,5-Dihydroxy-1-tetralone (S-isomer)
EINECS	Contact for details

Quality Control

Our (4S)-4α,5-Dihydroxytetralin-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.