Description

Sporidesmine CAS NO 22327-77-1 is a mycotoxin produced by certain fungi, primarily of the *Pithomyces* genus. This compound is of significant interest in agricultural and veterinary research due to its role as the causative agent of facial eczema, a serious liver disease in grazing livestock. Its study is critical for developing diagnostic tools and management strategies to protect animal health and ensure food safety. Researchers and analytical laboratories focused on mycotoxicology, animal health diagnostics, and feed safety are the primary users of this reference material.

Application

• Veterinary Diagnostic Research: Used as a certified reference standard for the detection and quantification of sporidesmin in biological samples (e.g., blood, bile, liver tissue) from affected animals.
• Feed and Forage Safety Analysis: Serves as a critical analytical standard for testing pasture grasses, hay, and silage for contamination by toxigenic fungi, helping to prevent livestock poisoning.
• Toxicological Studies: Employed in laboratory research to investigate the mechanisms of hepatotoxicity, bile duct occlusion, and photosensitization caused by sporidesmin exposure.
• Method Development and Validation: Essential for developing, calibrating, and validating analytical methods such as HPLC, LC-MS/MS, and ELISA for mycotoxin detection.
• Phytotoxin Research: Studied for its effects on plant physiology and pathology, contributing to broader ecological and agricultural science.
• Production of Antibodies and Assay Kits: Acts as a hapten for the production of specific antibodies used in immunochemical test kits for rapid field or laboratory screening.

Basic Information

Product Name	Sporidesmine
CAS No.	22327-77-1
Molecular Formula	C₁₈H₂₀ClN₃O₆
Molecular Weight	409.82 g/mol
Synonyms	Sporidesmin; Sporidesmin A; Pithomycolide; Facial Eczema Toxin; (3aS,5aR,9bS)-8-Chloro-9b-hydroxy-5a-(hydroxymethyl)-2,3,3a,5a,9b,10-hexahydro-2-methyl-3-methylene-7H-[1,4]oxazino[3,2-b]isoindolo[2,1-d][1,4]oxazine-7,11(6H)-dione
EINECS	Contact for details

Quality Control

Every batch of Sporidesmine is produced and handled under strict quality protocols to ensure identity, purity, and stability for research use. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with industry standards for reference materials. Certificates of Analysis (COA) detailing batch-specific results for identity, assay, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.