Description

1-(4-Bromophenyl)Pyrrolidine is a versatile brominated pyrrolidine derivative, a key organic intermediate prized for its role in constructing complex molecular architectures. Its value lies in providing a functionalized aromatic-pyrrolidine scaffold essential for pharmaceutical research and advanced material synthesis. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and ligand design.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrrolidine moiety.
• Ligand Synthesis for Catalysis: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials and liquid crystals due to its conjugated aromatic system.
• Chemical Biology & Proteomics: Utilized as a molecular probe or a fragment in fragment-based drug discovery (FBDD) campaigns.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	1-(4-Bromophenyl)Pyrrolidine
CAS No.	22090-26-2
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	4-Bromo-N-(pyrrolidin-1-yl)aniline; N-(4-Bromophenyl)pyrrolidine; 1-(p-Bromophenyl)pyrrolidine; 4-Bromophenylpyrrolidine; Pyrrolidine, 1-(4-bromophenyl)-; 4-Bromo-1-pyrrolidinylbenzene; 22090-26-2; 4-Bromo-N-pyrrolidinoaniline
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)Pyrrolidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.