Description

3-Formyl-5-Methoxybenzonitrile is a versatile aromatic nitrile and aldehyde derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This high-purity compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.
• Custom Synthesis Building Block: Provides a formyl and cyano handle for sequential functionalization in contract manufacturing and bespoke chemical production.

Basic Information

Product Name	3-Formyl-5-Methoxybenzonitrile
CAS No.	21962-46-9
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	5-Methoxy-3-formylbenzonitrile; 3-Cyano-5-methoxybenzaldehyde; 5-Methoxyisophthalaldehyde mononitrile; 3-Formyl-5-methoxybenzonitrile; 5-Methoxy-3-cyanobenzaldehyde; 3-Aldehyde-5-methoxybenzonitrile; Isophthalonitrile, 5-methoxy-3-formyl-; Benzaldehyde, 3-cyano-5-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Formyl-5-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent lot-to-lot performance. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.