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Diisopinocampheylborane CAS NO 21947-87-5


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CAS No.:21947-87-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Diisopinocampheylborane (CAS NO 21947-87-5) is a highly valuable chiral organoborane reagent, prized for its exceptional stereoselectivity in asymmetric synthesis. Its core value lies in enabling the production of enantiomerically pure intermediates, which are critical for developing pharmaceuticals and fine chemicals with high biological activity. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral building blocks.

Application

  • Asymmetric Hydroboration: A premier reagent for the enantioselective hydroboration of prochiral alkenes to yield chiral organoboranes.
  • Pharmaceutical Intermediate Synthesis: Key for constructing chiral centers in active pharmaceutical ingredients (APIs), especially for nervous system and cardiovascular drugs.
  • Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
  • Fine Chemical and Fragrance Manufacturing: Enables the creation of chiral molecules for high-value flavors, fragrances, and specialty chemicals.
  • Academic and Industrial R&D: A fundamental tool in methodological development for new asymmetric transformations in organic chemistry.
  • Material Science Precursor: Serves as a chiral precursor for advanced polymeric materials and liquid crystals.

Basic Information

Product Name Diisopinocampheylborane
CAS No. 21947-87-5
Molecular Formula C20H35B
Molecular Weight 286.30 g/mol
Synonyms DIP-Chloride; (1R)-(-)-Diisopinocampheylborane; (-)-Diisopinocampheylborane; (1R,2S,3R,5S)-(-)-Diisopinocampheylborane; B,B-Bis[(1R,2S,3R,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]borane; Ipc2BH; DIP-Chloride Borane Reagent
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Quality Control

Our Diisopinocampheylborane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling. Certificates of Analysis (COA) detailing specific results for purity, enantiomeric excess, and identity are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and hydrolysis. The container should be kept in a cool, dry, and well-ventilated area separate from incompatible materials. Due to its moisture-sensitive and easily oxidized nature, allow the container to reach room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance Colorless to pale yellow solution or solid
Identification (IR) Conforms to structure
Assay (NMR) ≥ 95.0%
Enantiomeric Excess (Chiral HPLC/GC) ≥ 99.0% ee
Solvent (if supplied as solution) Specified (e.g., Tetrahydrofuran, Hexanes)
Concentration (if supplied as solution) Specified (e.g., 1.0 M in THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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