Description

α-[4-(Trifluoromethyl)Phenyl]Benzhydryl Alcohol is a specialized fluorinated benzhydrol derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its unique trifluoromethylphenyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in stereoselective synthesis to control the configuration of new chiral centers.
• Advanced Polymer Chemistry: Acts as a monomer or chain modifier for creating specialty polymers with tailored thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorinated compounds and their properties.

Basic Information

Item	Details
Product Name	α-[4-(Trifluoromethyl)Phenyl]Benzhydryl Alcohol
CAS No.	21856-96-2
Molecular Formula	C20H15F3O
Molecular Weight	328.33 g/mol
Synonyms	α-(4-(Trifluoromethyl)phenyl)benzhydrol; (4-Trifluoromethylphenyl)diphenylmethanol; 1,1-Bis(phenyl)-1-[4-(trifluoromethyl)phenyl]methanol; α-(p-Trifluoromethylphenyl)benzhydrol; 4-Trifluoromethylbenzhydrol; [4-(Trifluoromethyl)phenyl]diphenylmethanol; (4-Trifluoromethylphenyl)benzhydrol; Diphenyl[4-(trifluoromethyl)phenyl]methanol
EINECS	Contact for details

Quality Control

Our α-[4-(Trifluoromethyl)Phenyl]Benzhydryl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.