Description

Sodium 2,2-Difluoro-2-(Trifluoromethoxy)Acetate is a high-value fluorinated organic salt that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both difluoroacetate and trifluoromethoxy groups, makes it a versatile precursor for introducing fluorine atoms into target molecules, enhancing their metabolic stability, lipophilicity, and binding affinity. This compound is essential for R&D and production within the pharmaceutical, agrochemical, and specialty materials sectors, where precise fluorination is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Polymer Modification: Imparts desirable properties like chemical resistance and low surface energy to specialty polymers and coatings.
• Organic Synthesis Reagent: Employed in research laboratories for constructing complex fluorinated molecules via nucleophilic substitution or coupling reactions.
• Fluorinated Surfactant Precursor: Used in the development of high-performance surfactants and surface treatment agents.

Basic Information

Product Name	Sodium 2,2-Difluoro-2-(Trifluoromethoxy)Acetate
CAS No.	21837-98-9
Molecular Formula	C3F5NaO3
Molecular Weight	202.0 g/mol (approx.)
Synonyms	2,2-Difluoro-2-(trifluoromethoxy)acetic acid sodium salt; Sodium 2,2-difluoro-2-(trifluoromethoxy)ethanoate; Acetic acid, 2,2-difluoro-2-(trifluoromethoxy)-, sodium salt; Difluoro(trifluoromethoxy)acetic acid sodium salt; TFM-O-CF2COONa
EINECS	Contact for details

Quality Control

Our Sodium 2,2-Difluoro-2-(Trifluoromethoxy)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, consistency, and compliance with customer specifications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment supports applications requiring GMP-grade materials for pharmaceutical development and other high-precision industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.