Description

4-Amino-3-Chlorobenzonitrile is a versatile aromatic nitrile building block characterized by its amino and chloro substituents, which provide distinct reactivity for advanced synthesis. This compound is valued for its role as a key intermediate in the production of complex organic molecules, offering a balance of functional group compatibility and structural diversity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic or fused-ring structures.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its halogen and amino groups for structural modification.
• Dye and Pigment Manufacturing: Serves as a building block for creating azo dyes and other complex colorants due to its aromatic amine functionality.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where its molecular structure can influence electronic properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating carbon-nitrogen bonds.
• Chemical Research & Development: A valuable reagent for exploring novel synthetic pathways and creating specialized compound libraries in medicinal chemistry.

Basic Information

Product Name	4-Amino-3-Chlorobenzonitrile
CAS No.	21803-75-8
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	3-Chloro-4-aminobenzonitrile; 4-Amino-3-chlorobenzene carbonitrile; 3-Chloro-4-cyanobenzenamine; 4-Cyano-2-chloroaniline; Benzonitrile, 4-amino-3-chloro-; 2-Chloro-4-cyanoaniline; 3-Chloro-4-cyanoaniline; 4-Amino-3-chlorophenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chlorobenzonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.