Description

(S)-(-)-n-(1-Phenylethyl)Phthalamic Acid CAS NO 21752-36-3 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and catalysts.

Application

• Chiral Auxiliary and Resolving Agent: Widely used in the optical resolution of racemic mixtures to isolate single enantiomers.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of enantiopure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drugs.
• Catalyst Ligand Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis, such as hydrogenation and cross-coupling reactions.
• Agrochemical Research: Used in developing chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Process Chemistry: A valuable tool in research laboratories for method development and studying stereoselective reaction mechanisms.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high optical purity for electronics or performance materials.

Basic Information

Product Name	(S)-(-)-n-(1-Phenylethyl)Phthalamic Acid
CAS No.	21752-36-3
Molecular Formula	C16H15NO3
Molecular Weight	269.30 g/mol
Synonyms	(S)-(-)-N-(1-Phenylethyl)phthalamic Acid; (S)-N-(α-Methylbenzyl)phthalamic Acid; (S)-N-(1-Phenylethyl)phthalamic Acid; (S)-(-)-1-Phenylethylphthalamic Acid; (S)-N-(1-Phenylethyl)phthalamate; NSC 163082; (S)-PEA-Phthalamic Acid
EINECS	Contact for details

Quality Control

Our (S)-(-)-n-(1-Phenylethyl)Phthalamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.