Description

1-Chloro-3,5-Di-(4-chlorobenzoyl)-2-deoxy-D-ribose is a specialized chlorinated ribose derivative, a key synthetic intermediate in the production of nucleoside analogs and other high-value pharmaceutical compounds. Its precise molecular architecture enables selective modifications critical for developing active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical sectors seeking to innovate in antiviral, anticancer, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Process Chemistry: Used in multi-step organic synthesis for introducing specific chlorinated ribose motifs into complex molecules.
• Research & Development: Serves as a key reagent in medicinal chemistry for structure-activity relationship (SAR) studies and new drug discovery programs.
• Fine Chemical Synthesis: Employed in the production of custom-designed, high-purity specialty chemicals for advanced applications.
• Bioconjugation: Potential use in modifying biomolecules due to its reactive chloro and benzoyl groups.

Basic Information

Product Name	1-Chloro-3,5-Di-(4-chlorobenzoyl)-2-deoxy-D-ribose
CAS No.	21740-23-8
Molecular Formula	C19H15Cl3O6
Molecular Weight	453.68 g/mol
Synonyms	1-Chloro-3,5-bis(4-chlorobenzoyl)-2-deoxy-D-ribofuranose; 2-Deoxy-1-chloro-3,5-di-O-(4-chlorobenzoyl)-D-ribose; 1-Chloro-2-deoxy-3,5-di-O-(p-chlorobenzoyl)-D-ribose; 1-Chloro-3,5-di-O-(4-chlorobenzoyl)-2-deoxy-D-ribofuranose; D-Ribose, 1-chloro-2-deoxy-3,5-bis(4-chlorobenzoate); 21740-23-8; NSC 404021
EINECS	Contact for details

Quality Control

Our 1-Chloro-3,5-Di-(4-chlorobenzoyl)-2-deoxy-D-ribose is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.