Description

Propionylmalonic Acid Diethyl Ester is a versatile diethyl ester derivative of malonic acid, serving as a key synthetic intermediate in organic chemistry. Its value lies in its bifunctional structure, which provides two distinct reactive sites for the construction of complex molecules, enabling efficient multi-step synthesis. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex carboxylic acid or ketone functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require specific malonate-derived structures.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and specialty polymers where controlled molecular architecture is essential.
• Academic & Industrial Research: Serves as a model substrate in methodological development for new C-C bond formation and esterification reactions.
• Flavor & Fragrance Industry: Acts as a precursor for the synthesis of certain esters and lactones that contribute to specific aroma profiles.

Basic Information

Item	Details
Product Name	Propionylmalonic Acid Diethyl Ester
CAS No.	21633-77-2
Molecular Formula	C10H16O5
Molecular Weight	216.23 g/mol
Synonyms	Diethyl Propionylmalonate; Diethyl 2-Propionylmalonate; Propionylmalonic Acid Diethyl Ester; 2-Oxopentanedioic Acid 1,5-Diethyl Ester; Ethyl Propionylmalonate; Malonic Acid, Propionyl-, Diethyl Ester; 1,5-Diethyl 2-Oxopentanedioate
EINECS	Contact for details

Quality Control

Our Propionylmalonic Acid Diethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.