Description

Bruceine E is a bioactive quassinoid compound, a key constituent derived from the seeds of Brucea javanica. This high-purity reference standard is essential for pharmaceutical research and development, particularly in the study of natural product-based therapeutics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors for applications in drug discovery, phytochemical analysis, and bioactivity studies.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material for the quality control and standardization of herbal extracts and finished pharmaceutical products.
• Drug Discovery & Development: Used as a lead compound or intermediate in pharmacological research targeting anti-cancer, anti-inflammatory, and anti-parasitic activities.
• Phytochemical & Analytical Research: Employed in method development and validation for HPLC, LC-MS, and other analytical techniques to identify and quantify quassinoids.
• Bioactivity Studies: Investigated in vitro and in vivo for its potential therapeutic effects, including cytotoxicity studies against various cancer cell lines.
• Nutraceutical Ingredient Standardization: Used to assay and standardize dietary supplements containing Brucea javanica extract to ensure potency and consistency.

Basic Information

Product Name	Bruceine E
CAS No.	21586-90-3
Molecular Formula	C₂₀H₂₈O₈
Molecular Weight	396.43 g/mol
Synonyms	Bruceine E; (1S,2R,6S,7R,11S,12R,14S)-7-(Furan-3-yl)-12-hydroxy-2,6,11,14-tetramethyl-4,9,15-trioxapentacyclo[9.5.1.0¹,¹⁴.0²,⁷.0⁶,¹¹]heptadec-16-en-8-one; Yadanziolide E; NSC 165563; A 102395
EINECS	Contact for details

Quality Control

Our Bruceine E is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.