Description

(1R,4Bβ,8Aβ,10Aα)-Tetradecahydro-7β-Isopropyl-1,4Aβ-Dimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, synthetically derived diterpenoid ester with a complex, rigid polycyclic structure. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical scaffolds, offering a versatile chiral building block. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory, antiviral, or anticancer research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct intricate diterpenoid and steroidal frameworks due to its defined stereochemistry.
• Asymmetric Catalysis Research: Serves as a substrate or a ligand precursor in the development and testing of new catalytic systems.
• Natural Product Synthesis: Critical intermediate for the laboratory synthesis of complex natural products and their analogues for biological evaluation.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals for agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Employed in chemical biology and medicinal chemistry programs to explore structure-activity relationships (SAR).

Basic Information

Product Name	(1R,4Bβ,8Aβ,10Aα)-Tetradecahydro-7β-Isopropyl-1,4Aβ-Dimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	21537-53-1
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	Methyl (1R,4aS,8aS)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene-1-carboxylate; Methyl Podocarpate; Methyl 13-isopropylpodocarpa-8,11,13-trien-16-oate (related isomer); Diterpenoid Methyl Ester; Podocarpic Acid Methyl Ester Derivative; (1R,4aS,8aS)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene-1-carboxylic acid methyl ester; 21537-53-1
EINECS	Contact for details

Quality Control

Our production of (1R,4Bβ,8Aβ,10Aα)-Tetradecahydro-7β-Isopropyl-1,4Aβ-Dimethyl-1α-Phenanthrenecarboxylic Acid Methyl Ester adheres to stringent quality protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting research and process standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.