Description

(+)-5-[(1E,3E)-1,3-Hexadienyl]-4-Methoxy-5-Methyl-3-[(E)-1-Oxo-2-Butenyl]Furan-2(5H)-One is a high-purity, optically active furanone derivative characterized by its complex dienyl and butenyl side chains. This compound is valued as a sophisticated chemical intermediate and building block for advanced organic synthesis, particularly in the development of novel molecular architectures. It is primarily sought by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and specialty materials, where its unique stereochemistry and functional groups enable the creation of complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), especially for complex natural product analogs and drug candidates.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its structural motifs can contribute to novel modes of action.
• Advanced Material Synthesis: Acts as a monomer or functional additive in the research of specialty polymers, liquid crystals, or organic electronic materials.
• Flavor & Fragrance Chemistry: Investigated as a potential intermediate for synthesizing complex, high-value aroma compounds due to its furanone core.
• Academic & Process Chemistry: Employed in methodological studies, asymmetric synthesis, and catalysis research within university and corporate laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chiral scaffold.

Basic Information

Product Name	(+)-5-[(1E,3E)-1,3-Hexadienyl]-4-Methoxy-5-Methyl-3-[(E)-1-Oxo-2-Butenyl]Furan-2(5H)-One
CAS No.	21494-09-7
Molecular Formula	C₁₈H₂₂O₄
Molecular Weight	302.37 g/mol
Synonyms	(+)-5-[(1E,3E)-1,3-Hexadienyl]-4-methoxy-5-methyl-3-[(E)-1-oxo-2-butenyl]furan-2(5H)-one; (5R)-5-[(1E,3E)-1,3-Hexadien-1-yl]-4-methoxy-5-methyl-3-[(1E)-1-oxo-2-buten-1-yl]-2(5H)-furanone; Optically active furanone derivative; Chiral hexadienyl furanone; (R)-enantiomer of the specified furanone
EINECS	Contact for details

Quality Control

Every batch of our (+)-5-[(1E,3E)-1,3-Hexadienyl]-4-Methoxy-5-Methyl-3-[(E)-1-Oxo-2-Butenyl]Furan-2(5H)-One is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and development. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.