Description

trans-2,3-Epoxybutane is a versatile chiral epoxide monomer with significant industrial utility. Its strained three-membered oxirane ring makes it a valuable electrophilic building block for synthesizing a wide range of fine chemicals and functional materials. This high-purity intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors seeking to introduce chiral centers or hydroxyl functionality into their target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug research.
• Agrochemical Synthesis: Used in the manufacture of chiral pesticides, herbicides, and plant growth regulators requiring specific stereochemistry for efficacy.
• Polymer & Resin Modification: Serves as a cross-linking agent or reactive diluent in epoxy resin systems, and as a monomer for producing polyethers and specialty polymers.
• Fine Chemical Production: Employed in asymmetric synthesis to create chiral alcohols, glycols, and other oxygenated compounds via ring-opening reactions.
• Flavor & Fragrance Industry: Intermediate for synthesizing specific chiral aroma chemicals and flavoring agents.
• Surface Active Agents: Building block for non-ionic surfactants and emulsifiers through reaction with fatty acids or alcohols.

Basic Information

Product Name	trans-2,3-Epoxybutane
CAS No.	21490-63-1
Molecular Formula	C4H8O
Molecular Weight	72.11 g/mol
Synonyms	trans-2,3-Epoxybutane; (2R,3R)-2,3-Epoxybutane; (2S,3S)-2,3-Epoxybutane; trans-2,3-Butylene Oxide; trans-2-Butene Oxide; 2,3-Epoxybutane (trans-); trans-Diepoxybutane (isomer); 2,3-Butene Oxide; EINECS 244-410-8
EINECS	244-410-8

Quality Control

Our trans-2,3-Epoxybutane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by GC and/or HPLC, to ensure it meets the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and ignition sources. Due to its nature as an epoxide and being easily oxidized (store under inert atmosphere), it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong acids, bases, and oxidizing agents. Recommended storage temperature: 2-8°C for extended periods.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Chiral Purity (enantiomeric excess)	≥ 99.0% ee
Moisture (KF)	≤ 0.1%
Specific Rotation	Contact for details
Refractive Index (n20D)	Contact for details
Density (20°C)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.