Description

1-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One is a specialized chlorinated ketone derivative of a benzo-fused medium-ring annulene, serving as a valuable synthetic intermediate in advanced organic chemistry. This compound is critical for research and development chemists who require high-purity, structurally complex building blocks for creating novel molecular architectures. Its unique fused-ring system makes it particularly relevant for applications in pharmaceutical development, agrochemical research, and materials science, where precise functionalization is key.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its chlorinated aromatic structure.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including cross-coupling reactions, nucleophilic substitutions, and ring-expansion chemistry.
• Materials Science: Investigated as a monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex polycyclic frameworks.
• Ligand Synthesis: Potential precursor for the creation of novel ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	1-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One
CAS No.	21413-75-2
Molecular Formula	C11H11ClO
Molecular Weight	194.66 g/mol
Synonyms	1-Chloro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one; 5H-Benzocyclohepten-5-one, 1-chloro-6,7,8,9-tetrahydro-; 1-Chloro-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulene; 1-Chloro-5-keto-6,7,8,9-tetrahydro-5H-benzo[7]annulene; 1-Chloro-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-one; 1-Chloro-5-oxo-6,7,8,9-tetrahydrobenzocycloheptene
EINECS	Contact for details

Quality Control

Our 1-Chloro-6,7,8,9-Tetrahydro-5H-Benzo[7]Annulen-5-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.