Description

3-(3-(Trifluoromethyl)Phenyl)Propanal is a versatile aromatic aldehyde building block characterized by a propanal chain and a trifluoromethylphenyl group. This structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF₃ group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Flavor & Fragrance Chemistry: Employed in the controlled synthesis of specific aromatic compounds for high-value fragrance applications.
• Organic Synthesis & Research: A versatile reagent for Friedel-Crafts reactions, reduction to alcohols, or reductive amination to yield valuable amine derivatives in academic and industrial R&D.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing aromatic and fluorinated units into specialty polymers to alter thermal and chemical resistance.

Basic Information

Product Name	3-(3-(Trifluoromethyl)Phenyl)Propanal
CAS No.	21172-41-8
Molecular Formula	C₁₀H₉F₃O
Molecular Weight	202.17 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]propanal; 3-(3-Trifluoromethylphenyl)propionaldehyde; 3-(α,α,α-Trifluoro-m-tolyl)propionaldehyde; m-Trifluoromethylphenylpropionaldehyde; 3-(3-Trifluoromethylphenyl)propanal; 3-(m-Trifluoromethylphenyl)propionaldehyde; 21172-41-8; 3-(3-(Trifluoromethyl)phenyl)propan-1-al
EINECS	Contact for details

Quality Control

Our 3-(3-(Trifluoromethyl)Phenyl)Propanal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.