Description

1-Bromobenzocyclobutene is a versatile brominated bicyclic organic compound that serves as a valuable building block in advanced synthetic chemistry. Its unique strained ring structure and reactive bromine substituent make it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to the development of novel polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of benzocyclobutene-containing active pharmaceutical ingredients (APIs) and bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with the benzocyclobutene moiety.
• Materials Science: A precursor for high-performance polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Academic and R&D: Used in fundamental organic chemistry research to study ring-strain reactivity and develop new synthetic methodologies.

Basic Information

Item	Details
Product Name	1-Bromobenzocyclobutene
CAS No.	21120-91-2
Molecular Formula	C8H7Br
Molecular Weight	183.05 g/mol
Synonyms	1-Bromobicyclo[4.2.0]octa-1,3,5-triene; Benzocyclobutene, 1-bromo-; 1-Bromo-1,2-dihydrobenzocyclobutene; Bromobenzocyclobutene; BCB-Br; 1-Bromobicyclo[4.2.0]octa-1,3,5-triene; 1-Bromo-1,2-dihydrocyclobutabenzene
EINECS	Contact for details

Quality Control

Our 1-Bromobenzocyclobutene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to traceability and documentation supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.